Pathogenesis and Immunity

The pathogenesis of a disease is the state of biological mechanism that leads to the diseased state. The term can also describe the origin and development of the disease, and whether it is acute or chronic. This process includes the pathogen that gets you sick, the method of how you got it, and what happened in the cells once it's in your body. It is the ability of the body to resist foreign harmful microorganisms, pathogens from entering it. Immunity involves both specific and nonspecific components. The nonspecific components of the immune system act like barriers or as eliminators for a wide range of pathogens irrespective of antigenic specificity. Other components of the immune system adapt themselves for each new disease encountered.

  • Pathogens and immune system: spread, persistence and transmission
  • Microbial adherence
  • Invasion of host cells and intracellular survival
  • Evasion of immune responses
  • Host interactions and system biology
  • Vaccine development

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